Bacteria serves tasty solution to plastic crisis

Biotechnology
People, Places and Planet
Sustainability
Bowl of vanilla icecream with sprinkles
Project contact
Dr Emma Elliott RTTP
Business Development Manager Schools of Biology and Chemistry College of Science & Engineering
Emma.Elliott@ei.ed.ac.uk

Scientists at the University of Edinburgh have devised a novel way of tackling the mounting issue of plastic pollution… by using bacteria to transform plastic waste into vanilla flavouring.

Plastic crisis

The global plastic waste crisis has created an urgent need to develop new methods of recycling polyethylene terephthalate (PET) – a strong, lightweight plastic derived from non-renewable materials such as oil and gas, and widely used for packaging foods and convenience-sized drinks. Approximately 50 million tonnes of PET waste is produced every year, causing serious economic and environmental impacts. While PET recycling is possible, existing processes create products that are less valuable, and continue to contribute to plastic pollution worldwide.

Tasty solution

In an effort to tackle the mounting plastic crisis, Dr Stephen Wallace and Dr Joanna Sadler from the University’s School of Biological Sciences made a remarkable discovery: the common bacteria E. coli can be deployed as a sustainable way to convert post-consumer plastic into vanillin.

Vanillin is the primary component of vanilla bean extract and is responsible for the characteristic taste and smell of vanilla. It is widely used in the food and cosmetics industries, as well as in the formulations of herbicides, antifoaming agents and cleaning products. Global demand for vanillin is growing rapidly and is projected to exceed 59,000 tonnes with a revenue forecast of $734 million by 2025.

The extraordinary transformation uses lab-engineered E. coli to turn terephthalic acid – a molecule derived from PET – into the high-value compound vanillin via a series of chemical reactions. The discovery, which has since been published in the journal Green Chemistry, has very exciting implications for the circular economy.

This is the first example of using a fully biological system to degrade and upcycle plastic waste into a valuable industrial chemical… The results from our research have major implications for the field of plastic sustainability and demonstrate the power of synthetic biology to address real-world challenges.
Joanna Sadler, First author and BBSRC Discovery Fellow, School of Biological Sciences, University of Edinburgh


The ground-breaking research, which was funded by a BBSRC Discovery Fellowship and a UKRI Future Leaders Fellowship, lays the foundation for further studies to maximise vanillin production towards industrially relevant levels.

Researchers say that the vanillin produced would be fit for human consumption but further experimental tests are required.