With over 180 group leaders and 500 research staff, our research is focused on two of the key challenges for 21st century neuroscience: How does the human brain develop and function across the lifespan, and how can it be protected and repaired?
Neuroscience at Edinburgh is carried across a series of cross-disciplinary centres, dedicated to the investigation of human diseases and developmental disorders from the bench to the clinic. Our integrated ‘discovery to delivery’ approach is underpinned by a rich collection of phenotyped clinical patient cohorts with associated biological data (e.g. brain imaging, DNA sequencing, stem cells and pathology samples). Together these provide a unique resource for health informatics and data science discovery. Our expertise in clinical trials design, management and delivery is world class and supported by dedicated Edinburgh Clinical Trials Unit which provides comprehensive facilities spanning trial planning, delivery and reporting, as well as research into improving the quality and efficiency of clinical trials. We have a strong track record of collaboration with external academic and industrial research groups to advance therapeutic discoveries in neuroscience.
Key areas of expertise
In vivo circuit physiology
We have exeprtise in combinations of virtual reality based behavioural assays, in vivo and ex vivo electrophysiology, two-photon calcium imaging, optogenetics, molecular and classical neuroanatomical methods, plus computational modelling.
Diverse animal models
From invertebrate (e.g. C elegans work
in Parkinson’s), rodent models (including a large number of
rat autism models), and large animal models (at the Roslin
Large and small clinical trials
Through the Anne Rowling Regenerative Neurology Clinic, and Edinburgh Clinical Trials we have facilities and expertise to provide infrastructure to design, plan and deliver clinical research studies across a varied portfolio of clinical specialities and methodologies.
Including outstanding MRI facilities
spanning rodent (9T), large animal, and human MRI. Click here for more information.
GMP cell therapy
Including seven high quality clean rooms
and dedicated GMP quality control laboratories for stem cell
characterisation and safety testing.
Facilities available at the University of Edinburgh for Neuroscience
- High-throughput Phenotypic Screening
Integrating the latest advances in induced pluripotent stem cell technology, high content screening, plate handling robotics, barcode sample tracking and multiparametric analysis, we have established a state-of-the-art human-based drug discovery platform for neuroscience.
- UK Zebrafish Screening Facility
For automated chemical and genetic in vivo screening of zebrafish. Includes an automated zebrafish embryo handling system which, combined with state-of-the-art imaging, enables rapid in vivo chemical screening, with follow up at the sub-cellular level.
Read about our current projects and success stories
Use of an existing drug on a new group of patients
A multinational healthcare company partnered with the University of Edinburgh for a clinical trial which demonstrated the benefit of using an existing drug on a new group of patients to improve their health outcomes.
Treatment for multiple sclerosis
The University of Edinburgh and a large multinational healthcare company are part of a collaboration which aims to develop a treatment for progressive Multiple Sclerosis.